Our Company - Proviva Pharma

From Montreal, Our Story Starts

Where?

Proviva Pharma is based in Montreal, Quebec, an exciting city and world-leading biotech cluster that is home to global pharmaceutical ventures, renowned research centers and advanced life science efforts.

Our Path and Goal

We’ve established a number of national and international collaborations in order to understand the health needs of people world-wide. Our goal is to revolutionize the global health industry with novel microbiome, probiotics and other health products. To accomplish this, we are engaged in:

Developing and marketing innovative probiotics for heart health, gastrointestinal diseases, bone, obesity, metabolic disease and others.
Understanding role of microbiome in health and diseases and focused on human and livestock health through the microbiome.
Stimulating healthy living and promoting active life, aging and longevity through microbiome.
Pushing the limits of understanding health in research and manufacturing sectors.
Offering next-generation therapeutics that are active, effective and affordable.
Working in collaboration with global partnerships in research, manufacturing and distribution of our current and future products.

Our Vision and Mission

Building a healthy environment that supports the development of individuals and communities.

Our vision is to become the global leader in microbiome, probiotics and other health products.

Our mission is to develop and distribute the most effective means for healthy living through microbiome innovations.

Today’s diet and lifestyle has greatly reduced the complexity of our gut microflora. Increasing populations of pathogenic bacteria are feeding on the over-consumed, simple sugars at the expense of fiber-feeding probiotic bacteria. This imbalance rears several whole-body physiological imbalances that ultimately lead to disease development:

Reduced immunity
Pro-inflammatory state
Dysregulated neurological signaling
Reduced bile metabolism
Reduced insulin sensitivity
Increase circulating blood glucose and triglycerides
Reduced breakdown of obesity-caused fats
Heightened cholesterol levels

Our Approaches:

To succeed at our mission, we took the following approaches:

1. Whole-body Health:

At Proviva Pharma, we believe that a healthy constitution begins in the gastrointestinal tract. It is our vision to develop ways to heal whole-body chronic diseases by re- establishing a healthy homeostasis in the gastrointestinal microflora.

2. Advance Medical Paradigms:

We seek to advance the modern medical paradigm of disease development by understanding the mechanisms of microflora-derived communication with the host. By implementing these mechanisms, we will evolve aspects of the gut microflora and their host-communication as therapeutic targets for disease.
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3. Alleviate Chronic Disease:

The influence of gastrointestinal health extends beyond our intestines. A healthy microflora impacts cardiovascular health, cancer development, neurological health, the development and integrity of our immune system, bone health and virtually every aspect of our longevity and healthy aging. Currently, it is accepted that a healthy gut is imperative to maintain overall vitality, but the power of utilizing the gut microflora as a preventative and therapeutic agent is still relatively untapped. At Proviva Pharma, we seek to realize the potential of our microscopic gastrointestinal inhabitants in healing chronic diseases.

Why Probiotics?

1. Probiotics May Assist in Intestinal Equilibrium of Friendly Microoganisms

Our gut microbiome can experience an imbalance of many harmful germs and less good bacteria. This disparity can occur due to disease, medicine such as antibiotics, unhealthy diet plans, and a great deal more. Repercussions can include digestion system issues, allergic reactions, psychological health problems, obesity, and far more.

Probiotics are real-time bacteria that help to recoup this imbalance. Probiotics contain “excellent” microorganisms. When taken in adequate quantities, probiotics can provide health and wellness advantages. These advantages are thought to occur from probiotics’ capacity to bring back the all-natural balance of digestive tract bacteria. Probiotics are generally located in fermented foods or taken as supplements. They also seem risk-free for the majority of individuals, which is great news!

2. Probiotics Can Help Treat and Avoid Diarrhea

Probiotics are commonly understood for their capability to calm down the bowels’ looseness or lower their intensity. Diarrhea is a common adverse effect of taking prescription antibiotics since antibiotics can negatively influence the equilibrium of good and bad microbes in the intestinal tract.

Many types of research suggest probiotic use to be associated with a minimized threat of antibiotic-associated diarrhea. In one research, scientists discovered that taking probiotics decreased antibiotic-associated diarrhea by 42%. Probiotics can also help with various other types of diarrhea that are not antibiotic-related. A tremendous testimonial of 35 types of research situated specific pressures of probiotics can decrease the period of transmittable diarrhea by around 25 humans resources. Probiotics minimized the danger of visitors’ diarrhea by 8%. They also reduced the complications of diarrhea from various other triggers by 57% in kids and 26% in adults. Effectiveness differs however, relying on the type and dosage of the probiotic taken.

Strains such as Lactobacillus rhamnosus, Lactobacillus casei, and the yeast Saccharomyces boulardii are mostly connected with a reduced risk of diarrhea. Overall, probiotics can lower the threat of diarrhea complications from a range of different causes.

3. Probiotic Supplements Can Improve Mental Health, Wellness and Other Health Issues

An increasing variety of research studies connect gut wellness and health to a state of mind and psychological health. The gut-brain axis is being further discussed to show the relationship between gut health and mental illnesses.

Both pet and human studies find that probiotic supplements can boost psychological well-being. An endorsement of 15 human research studies found supplementing Bifidobacterium and Lactobacillus pressures for one to two months can improve stress and anxiety, depression, autism, obsessive-compulsive problems (OCD), as well as memory.

One research study involved 70 individuals for six weeks. Those who ate 100 grams of probiotic yogurt daily or took a daily probiotic pill experienced benefits for general health and wellness, anxiousness, stress, in addition to depression. Benefits were additionally seen in another study of 40 people with depression. Taking probiotic supplements for 8 weeks lowered anxiety levels and likewise minimized C-reactive healthy protein (a pen of swelling) and hormonal agents such as insulin, contrasted to individuals that did not take a probiotic.

4. Particular Probiotics Can Help Maintain a Healthy Heart

Probiotics might help preserve your heart health by lowering LDL (” bad”) cholesterol and hypertension. Specific lactic acid-producing bacteria might lower cholesterol by breaking down bile in the gut. Bile is a naturally occurring liquid mainly constructed from cholesterol, aids food digestion. By breaking down bile, probiotics can prevent it from being reabsorbed in the gut and going into the blood as cholesterol.

According to five studies, consuming probiotic yogurt for 2-8 weeks reduced total cholesterol by 4% and LDL cholesterol by 5%. Another research study performed over 6 months found no changes in total or LDL cholesterol. However, the scientists did see a small surge in HDL (” outstanding”) cholesterol, which is a beneficial cholesterol that reduces the risk for heart disease. Consuming probiotics might also lower hypertension. A testimony of nine investigations found that probiotic supplements reduce blood pressure. However, in order to experience any type of advantages related to high blood pressure, supplements are required to go beyond 8 weeks and 10 million colony-forming systems (CFUs) daily. Routine supplement with probiotics may therefore have positive benefits on blood pressure.

Overall, probiotics may aid protect the heart by minimizing “poor” LDL cholesterol degrees in addition to modestly reducing high blood pressure.

5. Probiotics May Lower the Degree of Specific Allergies and Dermatitis

Particular probiotic pressures may lower the intensity of eczema in babies as well as youngsters. One research study uncovered dermatitis symptoms improved for infants fed probiotic-supplemented milk, contrasted to babies fed milk without probiotics. Another study followed young women that took probiotics during pregnancy. The newborns of the women had an 83% minimized threat of establishing dermatitis in the really first two years of life.

The web link between probiotics and reduced dermatitis severity is still weak. As so, further research is needed. Some probiotics might likewise lower inflammatory events in people with milk or dairy products’ allergic reactions. However, more studies are needed in this area of research as well.

6. Probiotics Can Help Reduce Symptoms and Signs of Particular Intestinal Problems

Over one million individuals in the USA manage inflammatory bowel disease, consisting of ulcerative colitis and Crohn’s disease. Particular sorts of probiotics from the Bifidobacterium and Lactobacillus stress have improved signs in individuals with moderate ulcerative colitis. Surprisingly, one research study discovered that supplementing with the probiotic E. coli Nissle was as helpful as medicine in preserving remission in people with ulcerative colitis. Nonetheless, probiotics show up to have little impact on symptoms of Crohn’s condition.

Probiotics might have benefits for different other bowel conditions. For example, early research study recommends they might assist with signs of irritable bowel syndrome (IBS). Probiotics have also been shown to reduce the hazard of severe necrotizing enterocolitis by 50%; Necrotizing enterocolitis is a deadly bowel disease that occurs in premature infants. Overall, probiotics could lower the indicators of digestive tract problems like ulcerative colitis, IBS, and necrotizing enterocolitis.

7. Probiotics May Help Boost Your Immune System

Probiotics might help give your body’s immune system a boost and hinder the development of damaging gut germs. Some probiotics have actually been revealed to promote the production of all-natural antibodies in the body. They may also boost immune cells like the IgA-producing cells, T lymphocytes, and natural cells. A study discovered that taking probiotics decreased the possibility as well as the duration of respiratory infections. Another research study, including over 570 children, showed that taking Lactobacillus GG decreased the degree of respiratory system infections by 17%.

Furthermore, the probiotic Lactobacillus crispatus has been revealed to lower the risk of urinary tract infections (UTIs) in females by 50%. Therefore, probiotics might help increase your body’s immune system as well as protect against infections.

8. Probiotics May Assist Slimming Down and Target Stubborn Belly Fat

Probiotics could help with weight loss through a variety of different mechanisms. Some probiotics protect against the absorption of dietary fat in the intestinal tract. The fat is then eliminated through feces instead of being kept in the body. Probiotics may also help you feel fuller for longer, shed significantly more calories, and store much less fat. This is partly set off by raising levels of specific hormonal agents, such as GLP-1.

Probiotics may similarly help with weight loss. One research study showed that females who took Lactobacillus rhamnosus for 3 months lost 50% more weight than women who did not take a probiotic. Another study of 210 individuals found that taking lowered dosages of Lactobacillus gasseri for 12 weeks brought about an 8.5% decrease in belly fat. However, not all probiotics may help in weight management. Surprisingly, some studies located particular probiotics, such as Lactobacillus acidophilus, can also bring about weight gain. In other words, specific probiotics can help you reduce weight, while other probiotics have been associated with weight gain.

9. Probiotics Can Enhance Animal Health and Feed

Probiotics have the potential to improve the overall well-being of animals by enhancing functionality and improving the quality of animal feed. Companion pets such as cats and dogs have shown to benefit from probiotics for a variety of conditions including allergic reactions, acute gastroenteritis, weight management and inflammatory bowel diseases (IBD). A study of twenty dogs with IBD showed an increase in regulatory T-cell markers and a restoration of balance to the gut microbiome in dogs treated with a probiotic formula containing Lactobacillus, Bifidobacterium and Streptococcus genera, compared to dogs treated with standard medicine.

Probiotics also can help improve animal feed and nutritional intake. Studies show Lactobacillus supplements to improve average daily gain and average daily feed intake of pigs while other studies show no significant effect. More research is therefore needed to establish the role of probiotics in animal nutrition. Nevertheless, probiotics are commonly used as supplements to animal feed for swine due to antitoxin and diarrhea possible benefits and immunomodulation.

Likewise, probiotics have shown to increase antibody production in broilers and encourage growth. A research study induced an Eimeria acervuline infection in broiler chickens and found a stronger immune response against the infection as well as higher IL-2 (growth factor) in Lactobacillus-fed broiler chickens compared to chickens not given the probiotic. Studies have shown similar results in cattle, sheep and goats for growth rate and production performance due to probiotic-supplemented animal feed. Overall, probiotics can enhance animal health and feed, and may act as an alternative to in-feed antibiotics for farm-raised animals.

10. Probiotics Can Be Used by Several Industries to Increase Market Value

Probiotics have shown to be valuable for a variety of industries including dairy, pharmaceutical, animal and other health sectors. The production of high-quality probiotic products can increase market value and revolutionize several industries.

The global market for industrial probiotics is projected to reach 3.5 billon dollars (USD) by 2026. Increasing use of Lactobacilli strain in dairy products is expected to fuel the industry, followed by Bifidobacterium, Streptococcus, Bacillus and other strains. Humans and animals are the main end-users of the probiotic market. More specifically, digestive diseases are a leading cause of probiotic supplement consumption. Similarly, animal end products such as animal feed will remain strong in the market. Overall, the production of novel probiotic formulas made using highly active and stable strains for a wide range of industry applications will drive the future of probiotics.

Why Proviva Pharma?

Proviva Pharma specializes entirely in friendly bacteria and supplies specific strains for your individual needs. Proviva Pharma is proud to be a reliable Canadian brand, and here are the reasons why:

1. Trusted Canadian and global partnerships

Our scientific companions are Canada’s most trusted institutions, including McGill University, Laval University, and the University of Alberta.

2. Created for you

We have always gone to the leading edge of creating probiotic supplements for specific requirements. This is essential because research shows that various sorts of friendly bacteria have different environments. We have options for the entire family including adults, women’s health, and children’s probiotic supplements available. We also have have probiotics for tailored needs, such as mental health, gut health, immune health, and many more. Whichever probiotic supplement is best for you, personalized dosage forms will be provided to fit your individual needs. Our product line also includes animal health probiotics designed for your favorite domestic and farm-raised animals. Likewise, our industrial probiotics can service all industrial needs such as dairy, cheese fisheries and other health sectors using our range in cultures provided.

3. Well-researched

Our bank has over a thousand of the most researched probiotic strains in the world. Our live culture pressures have also been extensively investigated in global leading laboratories. In addition, all of our probiotic and prebiotic supplements are approved for industry standards.

4. Easy to take

Our products come in various dosage forms to fit every lifestyle! They are conveniently available as capsules, dissolvable powders that you can mix with your favorite drink or food, and even as naturally flavored chewable. Our probiotic packs are also well-organized to be useful for human, animal and industrial uses.

5. Ideal for everyone

All our probiotic supplements are Non-GMO, Kosher, Halal, and Allergen Free. Suitable for vegetarian, dairy-free, gluten-free, soy-free, and vegan diets. They are made with 100% natural ingredients and are free from artificial colorings, flavorings, and additives.

6. Great Manufacturing Company

All our products are manufactured in US FDA- and Health Canada-approved GMP production plants in the US and Canada by our partner,

Biena. All of the Proviva Pharma probiotic products are manufactured under GMP conditions in a 55,000 sq. ft, state-of-the-art facility.

Our facilities are GMP certified, where the probiotic supplements are produced from strain vials to finished products in personalized dosage forms to fit Proviva Pharma’s needs. Our manufacturing process puts quality assurance first with over 150 QA checkpoints, complete traceability of lots and use of stable and viable cells.

Proviva Pharma probiotic products are manufactured in Montreal, Canada, in the heart of St-Hyacinthe’s Biotechnology Park. This area has been recognized globally by PwC and AURP as one of the top bio-clusters for food, veterinary, and environmental-focused health innovations. The region currently holds more than 400 manufacturing companies in agribusiness and biotechnology and is ranked one of Canada’s best and most suitable industrial dynamism locations.

7. We Care

We at Proviva Pharma care about the wellness and joy of everyone. We are committed to our continuous research to bring you the best and the most effective probiotic supplements for your whole-body health, the health of animals and future industry applications.

Go ahead and check our range of probiotic supplements to find the one that meets your needs, your favorite animal’s needs or the needs of your industry.

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